The Barbier-Type Alkylation of Carbonyl Compounds with Alkyl Halides Using Metallic Strontium
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چکیده
منابع مشابه
Photoinduced, copper-catalyzed alkylation of amides with unactivated secondary alkyl halides at room temperature.
The development of a mild and general method for the alkylation of amides with relatively unreactive alkyl halides (i.e., poor substrates for SN2 reactions) is an ongoing challenge in organic synthesis. We describe herein a versatile transition-metal-catalyzed approach: in particular, a photoinduced, copper-catalyzed monoalkylation of primary amides. A broad array of alkyl and aryl amides (as w...
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ژورنال
عنوان ژورنال: Journal of Synthetic Organic Chemistry, Japan
سال: 2006
ISSN: 0037-9980,1883-6526
DOI: 10.5059/yukigoseikyokaishi.64.845